30.06.2021
  • DEINOVE is intensifying its collaboration with the Max Mousseron Institute of Biomolecules (IBMM) and the Physical Measurement Laboratory (LMP) of the University of Montpellier to accelerate the discovery and identification of new antimicrobial molecules.

  • ATB-Discover aims to develop innovative analytical approaches based on the use of Ultra High Resolution Mass Spectrometry.

  • The European Regional Development Fund (FEDER) and the Occitania Region have granted €560K and €430K, respectively, to the ATB-Discover project over a 30-month period.

DEINOVE (Euronext Growth Paris : ALDEI), a French biotech company pioneering the exploration and exploitation of bacterial biodiversity to address the urgent and global challenge of antimicrobial resistance, announces its collaboration with the Max Mousseron Institute of Biomolecules (IBMM) and the Physical Measurement Laboratory (LMP) of the University of Montpellier for the co-development of new analytical approaches based on the use of Ultra High Resolution Mass Spectrometry, over a 30-month period. This project benefits from a €990K funding from the European Regional Development Fund (FEDER) and the Occitania Region.

The ATB-Discover partnership research project was selected in the framework of the call for proposals “Regional Research and Innovation Platforms” (PRRI), in line with the regional innovation strategy “Innovative and targeted therapies”.

ATB-Discover aims to complete and strengthen DEINOVE’s in-house analytical capabilities. This project is in total synergy with DEINOVE’s industrial strategy for the development of new antimicrobials, which was recently supported by two other independent expert committees (see France Relance[1] and Priority Research Program “Antibiotic Resistance”[2] press releases).

ATB-Discover also contributes to the territorial policy by federating a scientific, institutional and economic community committed to the societal challenges of MUSE “Montpellier University of Excellence: Nourish/Care/Protect”[3]. This innovative collaborative research project relies on a vast range of techniques and expertise in analytical chemistry, and more particularly in mass spectrometry, available at the Max Mousseron Institute of Biomolecules[4] and the Physical Measurement Laboratory[5].

ATB-Discover will accelerate the identification of active antimicrobial molecules in bacterial extracts at DEINOVE:

  • Better detection of molecules of interest based on increased sensitivity during analysis;  
  • Determination of the molecular formula of each molecule of interest enabled by the extreme precision of Ultra High Resolution;
  • Rapid determination of structures of unknown molecules using a dedicated software suite.  

“ATB-Discover will strengthen our interactions with highly qualified and internationally recognized scientists from the University of Montpellier. It will allow us to develop and implement innovative strategies using the most powerful state-of-the-art technology. The identification of the molecule responsible for the antimicrobial activity in an environment  that may contain several thousand molecules is certainly one of the most complex steps in the process. There is no doubt that this project will increase our capacity to discover active molecules and serve our priority goal: to bring new therapies to patients.”explains Georges GAUDRIAULT, Chief Scientific Officer of DEINOVE.

“We are pleased to be able to rely on the support of the European Union and the Occitania Region in the implementation of the ATB-Discover project. This funding is essential at a time when the world is more than ever driven by biotechnology companies in the finding of new treatments for multi-resistant bacteria”, adds Alexis RIDEAU, Chief Executive Officer of DEINOVE.

« The ATB-Discover project perpetuates a long-standing scientific collaboration with DEINOVE. The backing of the Occitania Region and the European Union has been decisive in financing the human and material resources necessary for the rapid progress of such ambitious research. The acquisition of very high technology equipment represents a sustainable investment to develop and promote a chemistry serving mankind and his environment within the University of Montpellier”, says Christine ENJALBAL, Professor at the Max Mousseron Institute of Biomolecules and Director of the Physical Measurement Laboratory of the University of Montpellier.

 

[1] https://urlz.fr/fZOk  

[2] https://urlz.fr/fZOl

[3] https://muse.edu.umontpellier.fr

[4] https://ibmm.umontpellier.fr

[5] https://lmp.edu.umontpellier.fr